0.1mg
Lyophilized · Research Grade
Purity
≥98%
Storage
-20°C
Format
Lyoph.
IGF-1 LR3
Long R3 IGF-1 analog with reduced IGFBP binding. Research-grade for IGF-1 receptor and proliferation studies.
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Research Grade
≥98% purity min.
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Product Description
IGF-1 LR3 incorporates an N-terminal 13 amino acid extension and Arg3 substitution that reduces binding to IGF binding proteins, extending bioavailability in research models. Produced by recombinant expression and purified by HPLC. Each vial contains 0.1mg.
Research Context
Research has examined IGF1R binding and downstream PI3K/Akt and MAPK/ERK signaling in cell culture models. The reduced IGFBP binding compared to native IGF-1 has been characterized in plasma protein binding assays.
Storage & Stability
Lyophilized. Store at -20°C. Protect from light. Stable for 18 months. Avoid repeated freeze-thaw cycles.
For research use only. Not for human or animal consumption. Not intended to diagnose, treat, cure, or prevent any disease. This product is sold for laboratory and research purposes only.